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Spinal Cord Tumors Treatment

What Are Spinal Cord Tumors?

Spinal cord tumors are abnormal growths of tissue found inside the bony spinal column, which is one of the primary components of the central nervous system (CNS). Benign tumors are noncancerous, and malignant tumors are cancerous. The CNS is housed within rigid, bony quarters (such as the spinal column), so any abnormal growth, whether benign or malignant, can place pressure on sensitive tissues and impair function.

Tumors that originate in the spinal cord are called primary tumors. Most primary tumors are caused by out-of-control growth among cells that surround and support neurons. In a small number of individuals, primary tumors may result from specific genetic disease (e.g., neurofibromatosis, tuberous sclerosis) or from exposure to radiation or cancer-causing chemicals.

The cause of most primary tumors remains a mystery. They are not contagious and, at this time, not preventable. Symptoms of spinal cord tumors include pain, sensory changes, and motor problems.

The first test to diagnose spinal cord tumors is a neurological examination. Special imaging techniques (computed tomography, magnetic resonance imaging and positron emission tomography) are also employed. Laboratory tests include the EEG and the spinal tap. A biopsy, a surgical procedure in which a sample of tissue is taken from a suspected tumor, helps doctors diagnose the type of tumor.

Is there Any Treatment?

The three most commonly used treatments are surgery, radiation and chemotherapy. Doctors also may prescribe steroids to reduce the swelling inside the CNS.

What Is the Prognosis?

Symptoms of spinal cord tumors generally develop slowly and worsen over time unless they are treated. The tumor may be classified as benign or malignant and given a numbered score that reflects how malignant it is. This score can help doctors determine how to treat the tumor and predict the likely outcome, or prognosis, for the patient.

What Research Is Being Done?

Researchers are studying brachytherapy (small radioactive pellets implanted directly into the tumor) and advanced drugs and techniques for chemotherapy and radiation therapy.

In gene therapy for spinal cord tumors, scientists insert a gene to make the tumor cells sensitive to certain drugs, to program the cells to self-destruct, or to instruct the cells to manufacture substances to slow their growth. Scientists are also investigating why some genes become cancer-causing.

Since tumors are more sensitive to heat than normal tissue, research scientists are testing hyperthermia as a treatment by placing special heat-producing antennae into the tumor region after surgery.

In immunotherapy, scientists are looking for ways to duplicate or enhance the body's immune response to fight against brain and spinal cord cancer.